Polymorphisms in ANGPTL4 link triglycerides with CAD

Melanocortin-4 receptor rs17782313 polymorphisms are associated with serum triglycerides in older Chinese women.

BACKGROUND AND OBJECTIVES MC4R (melanocortin-4 receptor) gene polymorphisms have been associated with serum triglycerides (TG) in Caucasians and Japanese, but no reports are available Chinese. The purpose of this study was to find whether there was an association of rs17782313 polymorphisms at the MC4R gene with serum TG in elderly Chinese. METHODS AND STUDY DESIGN 2,012 over 40 years partici...

Angiopoietin-like 4 (Angptl4)

Angiopoietin-like 4 (Angptl4) is a secreted protein modulating triacylglycerol homeostasis. Its transcription is induced by glucocorticoids, which act to elevate circulating Angptl4 levels during fasting. In investigating the role of Angptl4 in glucocorticoid action, we identified that in addition to its known ability to inhibit lipoprotein lipase, Angptl4 stimulates intracellular adipocyte lip...

Cytokine gene polymorphisms and development of CAD associated with CP infection.

Acute high-fat diet paradigms link galanin to triglycerides and their transport and metabolism in muscle.

To compare the effects of acute exposure to dietary fat to those of chronic exposure, Sprague-Dawley rats were given a high-fat diet (50% fat) or moderate-fat diet (25% fat) for 1 day, 2 h or 3 weeks. With measurements of various parameters, the high-fat diet for 21 days produced the expected changes of: (1) a significant increase in total caloric intake and dissected fat pad weights; (2) a ris...

Comparison of Adipose tissue fatty acide in CAD and non-CAD patients

since long term dietary fatty acide intake is reflected in the fatty acide composition of  Adipose tissue, this study was aimed to compare the adippose tissue fatty acide profile of angiography documented CAD (test)and non-CAD(control)  patients.the first group were 25 patients who underwent coronary artery bypass graft surgery in open heart surgery section of Shahid Beheshti hospital of Kerman...